Giants vs. Cowboys prediction, odds, spread, injuries, trends for NFL Week 10

A full betting preview for Sunday's Week 10 matchup between the New York Giants and Dallas Cowboys.
Oct 29, 2023; Arlington, Texas, USA; Dallas Cowboys wide receiver CeeDee Lamb (88)
Oct 29, 2023; Arlington, Texas, USA; Dallas Cowboys wide receiver CeeDee Lamb (88) / Kevin Jairaj-USA TODAY Sports

After suffering a hard-fought loss to the Philadelphia Eagles, the Dallas Cowboys return to Jerry World to play the New York Giants on Sunday.

Dallas had its two-game winning streak snapped last week in a five-point loss to the Eagles. But they should have much better luck against the Giants, who have dropped six out of their past seven games and lost starting QB Daniel Jones to a torn ACL.

Can the Cowboys keep pace with the Eagles in the NFC East? Or will the Giants finally snap their four-game road losing streak? Below, we’ll break down this Week 10 matchup and give our prediction using odds from DraftKings. 

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Giants vs. Cowboys Odds, Spread and Total

Giants vs. Cowboys Betting Trends

  • Giants are 1-4 ATS on the road this season
  • The UNDER is 7-0 in the Giants’ last seven games
  • Cowboys are 3-0 ATS at home this season
  • Cowboys are 11-0 straight up in their past 11 home games

Giants vs. Cowboys Injury Reports

Giants Injury Report

  • Daniel Jones - QB - OUT
  • Tyrod Taylor - QB - IR
  • Graham Gano - K - IR
  • Evan Neal - OT - Questionable
  • Jashaun Corbin - RB - Questionable

Cowboys Injury Report

  • Leighton Vander Esch - LB - IR

Giants vs. Cowboys How to Watch

  • Date: Sunday, Nov. 12
  • Game Time: 4:25 p.m. EST
  • Venue: AT&T Stadium
  • How to Watch (TV): FOX
  • Giants Record: 2-7
  • Cowboys Record: 5-3

Giants vs. Cowboys Key Players to Watch

New York Giants

Saquon Barkley: For the Giants to keep Sunday’s game close, they must continue to feed their star running back. Barkley had 113 total yards on 19 touches in last week’s 24-point loss to the Raiders. Since Week 6 against the Bills, the 26-year-old running back is averaging 24.3 carries per game. He will likely see upwards of 20-plus carries against the Cowboys as the Giants will turn the starting QB job over to rookie Tommy DeVito.

Dallas Cowboys

CeeDee Lamb: The 24-year-old wide receiver is coming off a phenomenal game against the Eagles last week. It did not matter who Philadelphia had covering Lamb, he still found a way to get open and make plays. He had 11 receptions (16 targets) for 191 yards. The former Sooners receiver has gone over 100-plus yards in three straight games and could make it four games against a less-than-stellar Giants’ secondary.

Giants vs. Cowboys Prediction and Pick

After coming up short against the Eagles, the Cowboys get a break facing a Giants’ offense that has struggled to score points this season (11.2 points per game). DeVito won’t change that, even though the Giants allowed him to throw the ball more. 

The last time we saw the Cowboys at home, they dismantled the Rams 43-20 with Matthew Stafford under center. A 16-point spread is a lot of points to lay in any NFL game, but we’ve seen Dallas blowout teams at home this season.

Game odds refresh periodically and are subject to change